The urine test for comprehensive hormones profile measures hormones and hormone metabolites (called conjugates) in a four-point urine sample. Measuring both hormones and their metabolites can give a better overall picture of hormone production. For example, a urine steroid hormone profile on someone with low salivary cortisol could show normal cortisol production, but high levels of metabolites. In other words, he/she is producing enough cortisol, it’s just getting broken down into its metabolites very quickly. There are also some metabolites that are important markers for breast cancer risk that can only be measured in urine.
With serum and saliva hormone spot-testing, it’s possible to track variations in hormone release throughout the day – what we call the circadian rhythm. In contrast, the standard 24-hour urine collection reflects the total hormone output in a 24-hour period. With the urine test for comprehensive hormones, you get the best of all methods.
Why Test Urine Steroids?
To get the best picture of overall steroid hormone production, or to see how supplemented hormones are being broken down by the body, a urine steroid hormone profile is the right choice.